A Diagnostic Dilemma: New Enhancing Suspicious Findings on Breast MRI Following Neoadjuvant Chemotherapy
نویسندگان
چکیده
Abstract Objective Evaluate the incidence and outcome of new enhancing findings on breast MRI after neoadjuvant chemotherapy (NAC). Methods This IRB-approved retrospective review included women with cancer undergoing to evaluate NAC response at our institution from January 1, 1998 March 3, 2021. Post-NAC MRIs given BI-RADS 4 or 5 were identified. Patients excluded if they lacked pretreatment insufficient follow-up, finding was a satellite primary tumor. Medical records imaging studies reviewed identify patients find characteristics outcomes. Results Over study period, 2880 post-NAC performed. Of 128 (4.4%), 35 suspicious found 32 MRIs, rate 1.1% (32/2880). Most characterized as nonmass enhancement (17/35, 49%), followed by mass (11/35, 31%), then focus (7/35, 20%), an average maximum dimension 1.3 cm (range 0.3–7.1 cm). New ipsilateral index in 20/35 (57%) cases. findings, 22 underwent image-guided biopsy (62%), 1 surgically excised (3%), 7 mastectomy (20%), stable resolved follow-up (8%), none malignant. Thirty-three benign (94%), two high-risk lesions (atypical ductal hyperplasia, radial scar) (6%). Conclusion are uncommon low likelihood malignancy. Further is warranted using multi-institutional data for this finding.
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ژورنال
عنوان ژورنال: Journal of breast imaging
سال: 2023
ISSN: ['2631-6110', '2631-6129']
DOI: https://doi.org/10.1093/jbi/wbad035